Arcuate Na + , K + - ATPase senses systemic energy states and regulates feeding 1 behavior through glucose - inhibited neurons 2 3
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چکیده
Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding 1 behavior through glucose-inhibited neurons 2 3 Hideharu Kurita, Kai Y. Xu, Yuko Maejima, Masanori Nakata, Katsuya Dezaki, Putra 4 Santoso, Yifei Yang, Takeshi Arai, Darambazar Gantulga, Shinji Muroya, Alan K. Lefor, 5 Masafumi Kakei, Eiju Watanabe, Toshihiko Yada* 6 7 Department of Physiology, Division of Integrative Physiology, Jichi Medical University School 8 of Medicine, Shimotsuke, Tochigi 329-0498, Japan. 9 Department of Neurosurgery, Jichi Medical University School of Medicine, Shimotsuke, 10 Tochigi 329-0498, Japan. 11 Department of Surgery, Division of Cardiac Surgery, University of Maryland School of 12 Medicine, Baltimore, MD 21201, USA. 13 Department of Psychiatry, Imamura-bunin Hospital, Kagoshima, Kagoshima 890-0064, Japan. 14 Department of Surgery, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 32915 0498, Japan. 16 17 Articles in PresS. Am J Physiol Endocrinol Metab (June 16, 2015). doi:10.1152/ajpendo.00446.2014
منابع مشابه
Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons.
Feeding is regulated by perception in the hypothalamus, particularly the first-order arcuate nucleus (ARC) neurons, of the body's energy state. However, the cellular device for converting energy states to the activity of critical neurons in ARC is less defined. We here show that Na(+),K(+)-ATPase (NKA) in ARC senses energy states to regulate feeding. Fasting-induced systemic ghrelin rise and gl...
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Hideharu Kurita,* Kai Y. Xu,* Yuko Maejima,* Masanori Nakata,* Katsuya Dezaki, Putra Santoso, Yifei Yang, Takeshi Arai, Darambazar Gantulga, Shinji Muroya, Alan K. Lefor, Masafumi Kakei, Eiju Watanabe, and Toshihiko Yada Department of Physiology, Division of Integrative Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan; Department of Neurosurgery, Jichi Medical...
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تاریخ انتشار 2015